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They compared 12,004 records of patients on a GLP-1 receptor agonist, like semaglutide or tirzepatide, to 15,221 using SGLT-2 drugs and 11,964 GLP-1 drug patients to 11,238 people taking DPP-4 inhibitors

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however, a severe exacerbation did occur in one of the non-adherent patients

"Sublingual" Drops, Lozenges, and Similar Formats Some online platforms market GLP-1 medications as sublingual drops, lozenges, or similar non-injectable formats

For a small subset of people, however, this stabilization might feel like flattening. FDA Evaluation: A Note on Mental Health Safety It is important to address the most serious concern: suicidal ideation