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(33)(45) Furthermore, obesity and inflammation are closely connected

While animal safety data is extensive and positive, no clinical safety data in humans has been published

Research areas include: Mitochondrial function Cellular energy transfer Aging-related cellular processes MOTS-c A mitochondrial-derived peptide

These often improve with lifestyle changes such as increasing hydration and cutting back on fatty or sugary foods

Clinicians considering off-label use must weigh emerging evidence against the lack of formal guidance, ensuring shared decision-making with patients and appropriate monitoring for both physical and psychological outcomes