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The safe limit for injectable products is 0.1 EU/mg
Frias JP, Nauck MA, Van J et al (2020) Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: a 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens
Cardiovascular outcome studies have shown cardiovascular advantages associated with certain GLP-1 receptor agonists, especially in those with pre-existing cardiovascular illness
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