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In vivo rat models of OVA-induced asthma demonstrated significant dose-dependent (100 mg/kg and 200 mg/kg) reductions in inflammatory cells in bronchoalveolar lavage fluid (BALF), lung inflammation scores, and NF-B signaling activating promoted by IgE production [57]

However, even with supporting evidence that patients with epilepsy have shown reduced levels of serum vitamin C [205], no clinical study reporting on the efficacy of vitamin C interventions in epilepsy exists

The vial format supports precise dose-response studies in cell-culture and animal models of NNMT inhibition and adipose-tissue metabolic regulation

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