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The brown algae are also known endogenous producers of a variety of polysaccharides, including alginates, fucoidans, and laminarans, which exhibit diverse therapeutic properties with relatively low toxicity [114,115,116]

Others who have difficulty absorbing nutrients may also have low B12 levels such as individuals who have had gastric bypass surgery or who have certain digestive disorders

Though these agents do increase arousal threshold in OSA with a modest improvement OSA severity [86, 87], they may have the potential for neurological depression and worsening of hypoxemia associated with OSA at higher doses

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