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A method for synthesizing semaglutide is characterized in that ionic liquid is used as a hydrophilic Linker to be coupled to solid-phase resin, then the ionic liquid is sequentially connected with corresponding amino acids in a semaglutide sequence through a solid-phase synthesis method, and the semaglutide fine peptide is obtained through cracking and purification

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Fate of cobalamins in humans following oral and intramuscular administration of cyanocobalamin, hydroxocobalamin, adenosyl-cobalamin and methylcobalamin

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10.1007/s13311-021-01018-5 7 BuT.SunZ.PanY.DengX.YuanG