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Immediately discontinue 5-amino-1MQ and return to tirzepatide monotherapy until symptoms resolve
"MOTS-c can significantly enhance physical performance in young, middle-age, and old mice." Reynolds et al., Nature Communications , 2021 [3] The ceiling on all of this is the same ceiling every mitochondrial peptide hits: the outcome data is rodent data
Chandy estimates that 1 in 10 people experience this effect
From the preclinical data for putative benefits there were also important side effects noted
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