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Moreover, interventions aimed at enhancing mitochondrial biogenesis or promoting ROS clearance also attenuate inflammasomes activation (186, 187), suggesting that the presence of actionable interventional points within the interaction between energy metabolism and neuroimmune responses (188)

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It will depend on the ability to connect multiple sources of evidence, including: Clinical trial data Real-world clinical data Patient-reported outcomes Biomarker and genomic information Healthcare utilization data Digital health technologies The goal is not to replace randomized clinical trials but to complement them, creating a more complete picture of how therapies perform in real-world healthcare settings

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Multiple sessions are usually required, making the total treatment costs vary significantly