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30% Argireline (Acetyl Hexapeptide-8) Clinically studied at a 10% concentration of a 1% solution to visibly reduce wrinkle depth appearance by 30% over 30 days

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Whereas little VEGF mRNA expression was detected in early anagen (day 1) hair follicles or in interfollicular epidermal keratinocytes, VEGF mRNA was highly expressed in follicular keratinocytes during mid-anagen (days 5 and 8), predominantly in the middle third of hair follicles (Figure 2a) where perifollicular angiogenesis was most prominent

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And the form of copper peptide most studied (GHK-Cu) works through cellular signalling, which means it can surface underlying skin activity rather than just sitting on the surface

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