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4 Conclusion and future perspectives More than 50 natural polysaccharides have been documented to improve oxidative stress, by regulating mitochondrial function, free radical levels, oxidase content, and Nrf2/HO-1, and AGEs/RAGE pathways in diabetes

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Diseases associated with mutation of transcription co-activator families Considering the compendium of previously stated facts on transcriptional co-activators, it is now quite evident that co-activators are indispensable for establishing homeostasis during gene expression

Recent research suggests that reduced glutathione may be an even more effective antioxidant than vitamins C and E, and it is considered the master antioxidant

T2D is primarily caused by obesity, a sedentary lifestyle, and hereditary variables, which are accountable for the altered glucose homeostasis observed in T2D [19]