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In the 72-week study of more than 1,600 overweight or obese adults with Type 2 diabetes, those who received the 36-milligram highest dose of orforglipron on average shed 10.5% of their weight, or about 23 pounds, versus 2.2% for those who received a placebo, achieving the main goal of the trial

Most people with private insurance may pay from $25 to $100 each month

For many, this medication is most effective when combined with healthy lifestyle changes, such as improved diet and regular exercise

Understanding a patient's GLP-1 response can enhance the customization of diabetes and obesity treatments, ultimately improving patient outcomes

Also, avoid meals that are high in refined carbohydrates (or generally unbalanced), as these can cause a rapid spike in blood glucose, and work against efforts to manage your blood sugar