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To that end, we systematically reviewed cartilage repair clinical trials to identify common exclusion criteria and reviewed the literature to identify emerging regenerative approaches that are poised to overcome these current exclusion criteria

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They upregulate growth factor receptors

Oncotarget 7(25):3846738486 Shaaban S et al (2016) Targeting bone marrow to potentiate the anti-tumor effect of tyrosine kinase inhibitor in preclinical rat model of human glioblastoma

IPR Filings: An Alternative Path for Generic Challenges Generic manufacturers are increasingly utilizing inter partes review (IPR) to challenge the validity of patents alongside ANDA filings