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This occurs in part through mechanical grinding of large clumps of food into smaller pieces for passage into the intestines

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Certain prescription medications, including antacids and anti-diabetic medicines like metformin can cause vitamin B12 deficiency An endocrine-related autoimmune disorder, such as thyroid disease or diabetes Eating a vegetarian or vegan diet and excessive consumption of alcohol Certain gastrointestinal disorders, such as Crohns disease or Gastric bypass surgery or removal of part of the stomach Brain related disorders such as anxiety, depression, irritability and even poor concentration and general restlessness Heart and blood-related problems, increased risk of infections, improper growth in children and complication during pregnancy If you are a strict vegetarian, take vitamin B12 supplements

Systemic bioavailability with standard oral forms is very low Oral vs