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10.3389/fimmu.2020.01229 Front Immunol

All experiments were performed in triplicate

MAJEWSKI, T., PODGORSKI, W., BIALKOWSKI, Z., & TYCZKOWSKI, J

Rhonda Patrick: I think the take home there is a lot of people with a darker skin living in sub-Saharan Africa or people living in India with darker skin or in the Philippines, these equatorial regions where there's, you tend to see darker skin because it's protection from the burning rays of the sun

While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51