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For instance, its extract significantly inhibits the lipopolysaccharide (LPS)-induced transcription of inflammatory cytokines (TNF-, IL-1 and IL-6) in RAW 264.7 cellsa well-established in vitro model for innate immune screening (Zhao et al., 2021)

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Barbosa, A

(January 2010)

While knockdown of SNX1 or SNX2 resulted in vacuolar mislocalization and enhanced degradation of GFPVSR2, it remains unclear whether VSRs constitute direct cargo of SNX proteins