Medication adjustments may be considered in consultation with prescribing clinicians: Dose reduction : Lowering the Ozempic dose may reduce symptom severity whilst maintaining some glycaemic benefit Slower titration : Increasing the dose more gradually than standard protocols may improve tolerability Prokinetic agents : In the UK, medications such as metoclopramide are generally restricted to short-term use (maximum 5 days) due to neurological side effect risks
However, doses of zinc in cold remedies can be in excess of what is safe
and the precision medicine and clinical genetics experts contextualize the PRS alongside other biomarkers, analyzing genetic predisposition in relation to the epigenetic burden of lifestyle, diet, and supplementation factors (Table 3)
If itching is intense, persistent, or accompanied by hives, rash, or swelling, contact your prescriber immediatelythese may signal a true allergic reaction requiring medication discontinuation or switching to a different GLP-1 compound or delivery method
If side effects remain severe beyond this period, a clinical review to assess whether the current dose is appropriate is recommended
