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380 Another primary astrocytopathy linked to dysregulated iron homoeostasis is aceruloplasminemia, an autosomal recessive neurodegenerative disease caused by a loss of function mutations of the gene encoding ceruloplasmin, an enzyme that converts ferrous iron to ferric

Interestingly, arachidonic acid is also a ligand of PPARs (118) and can inhibit the growth of lung cancer cells by activating PPAR and lipid peroxidation (119, 120)

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