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Concentrations above 3 mg/mL exceed solubility limits and cause peptide precipitation, while concentrations below 0.5 mg/mL require larger administration volumes that exceed the nasal cavity's absorption capacity (approximately 150 L per nostril)

Its stability in gastric acid radically distinguishes BPC-157 from most naturally occurring proteolysis-sensitive peptides

Jeulin C, Lewin LM

Therefore, even though peroxisomal -oxidation may have been up-regulated in the d-carnitine group, this would have been insufficient to compensate for the depressed mitochondrial -oxidation of FA

AMG-458 significantly enhances the radiosensitivity of H441 [75]