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Both the glycocalyx and junctional proteins resist solute entry, promoting endothelial cell connectivity [44]

Zygoura, V

An increased V d would tend to prolong clearance time

There is the ophthalmic vein, angularis vein, facial anterior and posterior vein, and facial vein, or through cerebri superior veins, sinus cavernosus, sinus petrosus superior and inferior, sinus transversus, through the jugular external vein, subclavia vein through the superior caval vein, retrograde filling of both jugular external veins and both superior caval veins with vertebral veins

Cisplatin induces BDNF downregulation in middle-aged female rat model while BDNF enhancement attenuates cisplatin neurotoxicity