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Furthermore, decreased NRP-1 partially inhibited the adhesion capacity of podocytes and impaired cellular reorganization skeleton, which may further influence podocyte injury in DKD and lead to proteinuria (72)

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The mRNA expressions of tumor necrosis factor- (p = 0.004) and interleukin-1 in peripheral blood mononuclear cells were downregulated (p = 0.046) in the liraglutide-treated group