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Cobalamins circulate bound to serum proteins called transcobalamins (TC) and haptocorrins

Short telomeres have been associated with accelerated aging, AD, diabetes, heart disease, cancer, and other medical conditions

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The two processes are mechanistically linked and each amplifies the other

We then compared free cysteine thiol levels between WT and mutant chondrocytes and observed no difference between the two genotypes during proliferation, but free cysteine thiols were increased in G6PDH-null chondrocytes compared to WT chondrocytes during differentiation, suggesting decreased oxidative protein folding (Fig