Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
doi: 10.1038/nrdp.2016.57 145 AstapovaOMinorBMNHammesSR
By activating GLP-1 receptors, Trulicity helps to regulate blood sugar levels, increase feelings of fullness, and slow down the emptying of the stomach, all of which contribute to weight loss
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Others enhance ovulation by supporting follicle maturation, decreasing local oxidative stress, or improving endometrial receptivity