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Factors influencing recovery time include: Duration of treatment : Longer exposure to semaglutide may be associated with more prolonged symptom resolution Symptom severity : More severe gastroparesis typically requires longer recovery periods Underlying conditions : Pre-existing diabetic neuropathy or gastric motility disorders may delay or limit recovery Dose : Higher doses of Ozempic may result in more pronounced and persistent effects Patients should be counselled that improvement is typically gradual, and realistic expectations should be set regarding the recovery timeline

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However, it should be noted that GSH at high concentrations (e.g., 30 mM) induces morphological changes in HFF-1 cells (Supplementary Figure S1E)

The activity of cystathionine -lyase (CSE) in the liver was determined by -ketobutyrate generation as description of previous studies with modification [27]

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