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A subset of patients who use GLP-1RAs experience HS flares, which points to a complex immunological reaction that differs based on individual immune profiles [62,65]

The higher the dose of the GLP-1 agonist, the more extreme the effects

Therefore, inhibiting CAR8 could be a promising strategy for improving GLP-1 secretion, a new approach to treating diabetes [143]

However, people who want to achieve maximum weight loss may want to consider injected obesity drugs like Wegovy HD and Zepbound, which produce more dramatic weight loss results than FDA-approved GLP-1 pills, Jay adds