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a plan for glucose self-monitoring and possible dose adjustment of these medicines should be agreed in advance
[13] [14] The UK Chief Medical Officers recommend at least 150 minutes of moderate-intensity activity or 75 minutes of vigorous-intensity activity weekly, along with strength exercises on two or more days
Further action may be necessary
The explanation for the discrepancy in the reduction of MACE in patients treated with SGLT2i in DECLARE-TIMI 58 suggests that the benefits of SGLT2i may be more pronounced in patients with a higher risk of cardiovascular disease
It targets the brains reward and hunger circuits rather than the central nervous systems stimulant receptors, so most patients describe the effect as quieter cravings rather than a jolt of energy
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