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PMID 38634551

The FDA's 2022 guidance on surrogate endpoints in musculoskeletal diseases accepts dual-energy X-ray absorptiometry lean mass combined with functional measures (grip strength, chair-stand test) as co-primary endpoints 22

For AutoDock Vina, the grid box was setting up with a range spacing of 0.897 , number of points in x, y and z dimensions as 52, 54, and 70 respectively and center grid box for x, y and z as 173.571, 198.031, and 203.573 respectively for the ATD of AtGLR3.3

It was given on its own (monotherapy) at a dose of 200300 mg daily for 4 weeks

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