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GLP-1 Receptor Agonists: A Different Class of Weight Loss Medication Semaglutide and tirzepatide belong to the glucagon-like peptide-1 receptor agonist family, medications that mimic natural hormones controlling blood sugar and appetite
Specifically, semaglutide increases phosphorylation of GSK3 at Ser9 (inhibiting its activity) and modulates Drp1 phosphorylation at Ser616 and Ser637, leading to reduced mitochondrial fission and preserved membrane potential
10.1038/cddis.2013.44 52 SaengerA
[103] Bersani, F.S
Instead of worrying about the number you are seeing on the scale, note other positive changes in your body after weight training such as increased strength, improved energy, and a leaner body shape
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