glp-1 news nov 2025 November in review: breakthroughs, UPFs under fire, Novonesis advances healthy longevity Wegovy maker Novo Nordisk makes

Several plant extracts have emerged as promising candidates in enhancing GLP-1 activity or mimicking its metabolic benefits

JAMA 332 , 910 (2024)

Ludvik B, Giorgino F, Jdar E et al (2021) Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

In many ways, your microbiome acts like a metabolic control panel influencing hunger, satiety, and energy regulation

Patients prescribed GLP-1 medications for diabetes or weight management have reported unexpected reductions in their desire to consume alcohol, with some describing a complete loss of interest in drinking