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This discovery led to the off-label use of topiramate for weight loss, which means doctors sometimes prescribe it for this purpose even though it is not officially approved for weight management by regulatory bodies like the FDA

Nqakala ZB, Sibuyi NRS, Fadaka AO, Meyer M, Onani MO, Madiehe AM

Those are precisely the questions the larger, longer Phase 3 TRIUMPH program is designed to answer, which is why an approval decision waits on it

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