At a poster spotlight session at the 2025 San Antonio Breast Cancer Symposium , researchers presented their recent findings on the effects of GLP-1s on people with breast cancer
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The medicine has progressed through Phase 2 clinical trials , where participants achieved: Dose-dependent weight loss of up to 24.2% after 48 weeks at higher doses 83% of participants at the maximum 12 mg dose losing 15% or more of their body weight All patients taking 8 mg or above are achieving at least 5% weight loss Larger Phase 3 trials are now underway to confirm these findings in broader, more diverse patient groups and to build longer-term safety data
Balancing GLP-1 Clinical Benefits with Financial Sustainability Pain Point : Plan sponsors are challenged to provide access to promising new medications while also controlling costs for both the plan and employees
Then there is the glucagon receptor, which is unique to retatrutide among the current generation of weight loss peptides