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High doses might make optic nerve damage worse

Current Opinion in Lipidology

The reason the framing matters so much is that a reader who accepts GHK-Cu improves skin as a route-neutral fact can be quietly led to a conclusion the evidence never established that pushing the same molecule in through a needle must do at least as much as rubbing it on

Dietary Antioxidants in the Treatment of Male Infertility: Counteracting Oxidative Stress

Because the peptide occurs naturally in human plasma (at roughly 200 ng/mL in young adults, declining to approximately 80 ng/mL by age 60), topical supplementation essentially restores youthful local concentrations in treated skin