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Akkermansia generates the postbiotics propionate and p9 which induce GLP-1 production

While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists

A healthcare provider can offer advice on which option is safest

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When excess body weight decreases, the heart requires less effort to pump blood, naturally reducing pressure in the arteries