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Conclusions A 90-day L-carnitine therapy in patients with nonalcoholic steatohepatitis and obesity improves clinical symptoms, reduces liver markers (ALT by 3.3 times, AST by 3.0 times), decreases cholestasis markers (-glutamyltransferase by 2.2 times, ALP by 2.06 times), and reduces mesenchymal inflammation (thymol test by 3.3 times)

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Gut hormone secretion experiments Secretion experiments were carried out within 24 h of plating

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252 Evidence suggests that tirzepatide improves obstructive sleep apnea primarily through a reduction of body weight, with improvements proportional to the degree of weight loss achieved