Funding Open access funding provided by Universit degli Studi di Brescia within the CRUI-CARE Agreement
Here's the quick version: For a 10mg vial: Add 2mL of bacteriostatic water (BAC water) this gives you 5mg/mL For a 0.25mg dose: draw 5 units (0.05mL) on a U-100 insulin syringe For a 0.5mg dose: draw 10 units For a 1mg dose: draw 20 units For a 20mg vial: Add 4mL BAC water same 5mg/mL concentration, same dose math above Injection technique: SubQ injection pinch the skin at belly, thigh, or upper arm 31g or 32g insulin needle ( inch length is fine for subQ) Inject slowly, hold for 5 seconds before withdrawing Refrigerate after reconstitution stable 4-6 weeks in the fridge Realistic Expectations for Weeks 1-12 Here's what most people experience on a conservative titration, assuming reasonable diet and some exercise: Weeks 1-2: Minimal weight change
Shots No needles this is huge for some people Taking a daily pill feels normal to most patients Doesnt need refrigeration Cost is similar to the injection The Challenges You must take it every single day, first thing in the morning The timing is picky empty stomach, minimal water, wait 30 minutes before eating Not quite as powerful as the shot Some people get more burping (I know, weird, but it happens) We dont have proof yet that it protects your heart like the injection does Now, About Those GLP-1 Patches Everyones Talking About GLP-1 Patches Everyones Talking About Okay, lets be real here
Hypoglycaemia (low blood sugar) is uncommon with GLP-1 receptor agonists when used alone, as they work in a glucose-dependent manner
Some protocols may start at 1 mg, but 2 mg is most common
