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have a financial interest related to this research, including patents and pending patents covering senolytic drugs and their uses that are held by Mayo Clinic

Alhagi camelorum Fisch polysaccharide (aAP) boosts spleen and thymus indices in mice, stimulates serum lgG and intestinal lgA antibodies, enhances intestinal cytokines, improves intestinal villi and crypt morphology, upregulates tight junction proteins (ZO-1 and Occludin), and increases intestinal immune cells (IELs and IgA + cells)

The administration of a synthetic peptide (FOXO4-DRI = FOXO4-D-Retro-Inverso) to avoid the interaction between FOXO4 and p53 leads to a decrease of irradiated-induced senescent fibroblasts viability

Motilin agonists

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