Consistency builds metabolic adaptation and muscle, both of which preserve your weight loss and improve insulin sensitivity well after you finish treatment
Thus, no evidence currently indicates that patients with HFrEF benefit from the administration of GLP-1RAs, but rather, the increased arrhythmias and death are concerning
Best for: GLP-1 users who want an easy daily routine, people strength training, anyone who struggles to hit protein consistently
These medications may not be appropriate for everyone, so its important to talk with your provider about the pros and cons
Orforglipron (branded as Foundayo) is the first small molecule GLP-1 receptor agonist, distinguishing it from peptide-based options like semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound)