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The oral version was previously available for diabetes management (under the brand name Rybelsus), but this new FDA approval specifically authorizes a high-dose oral formulation for chronic weight management

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Triggers include: Genetics (most common) Dry or sensitive skin Atopic tendencies Climate changes and winter dryness Because it is rooted in keratin plugging hair follicles , KP responds best to treatments that target the hair follicle itself not acne medicines

194 The pathophysiology is thought to involve ischemia due to microangiopathy and metabolic disturbances

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