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It is also the most damaging

However, dual immunofluorescence for GLP-1R and the marker for CSF-contacting neurons, PKD2L1 33 , was not feasible, because both antibodies are detected with anti-rabbit secondary IgGs (the GLP-1R antibody is a rabbitized mouse antibody)

Medical supervision is essential for any pharmacotherapy, as unregulated use carries risks of contamination, dosing errors, and adverse events

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Clinical trials show sustained weight loss over 68 weeks, with greater reductions in patients who maintain diet and exercise changes alongside treatment