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It should not be used in patients with inflammatory bowel disease and diabetic gastroparesis
However, when ascorbate is administered intravenously or intraperitoneally the tight controls are bypassed, and pharmacologic millimolar plasma concentrations of vitamin C can easily be achieved
The importance of being CG-rich and the curious case of Sox2 Transcription factors involved in adult neurogenesis are single-exon genes, for example, Sox2 , Sox4 , and Sox11 , or two-exon genes, for example, Ngn2 , NeuroD1, and NeuroD2 , that are embedded in long stretches of high CG densities (CpG islands)
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