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[DOI] [PubMed] [Google Scholar] 97.James C, Pugh T, Johnson AL, Jenkins ATA

Our findings highlight the therapeutic potential of GLP-1RAs for managing BBS-associated metabolic dysregulation, indicating that further investigation for clinical application is warranted

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Retatrutide is a next-generation peptide designed to act on three key metabolic hormone pathways simultaneously: GLP-1 (Glucagon-Like Peptide-1) GIP (Glucose-Dependent Insulinotropic Polypeptide) Glucagon receptors Because of this triple-agonist action, retatrutide works systemically influencing the brain, liver, pancreas, fat tissue, and inflammatory pathways at the same time.This multi-targeted design is what separates retatrutide from earlier peptides and medications

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