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According to president of the American Society of Anesthesiologists* (ASA) Michael Champeau, MD, patients [should] stop taking weight-loss drugs such as Ozempic and Wegovy prior to surgery particularly procedures using general anesthesia due to the increased potential for complications like delayed stomach emptying and gastric content aspiration

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d ) Schematic of the proposed mechanism of sulfonyl fluoride conversion to sulfinic acid triggered by nucleophilic thiol groups of reducing agents, such as DTT ( in vitro ) or GSH (in cells)

The FDA's April 30, 2026 proposal to exclude semaglutide from the 503B bulk substances list - currently in public comment through June 29, 2026 - would, if finalized, close large-scale outsourcing-facility compounding of semaglutide from bulk entirely