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The rectal administration is also beneficial for patients who may have difficulty swallowing pills or for those who have gastrointestinal issues that could interfere with the absorption of oral medications

(2024) further proposed a new concept of H 2 S metabolic balance in cancer: during early tumorigenesis, oncogenic mutations may induce a compensatory upregulation of H 2 S-degrading enzymes like SQOR to protect cells from H 2 S toxicity

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