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Another study published in the American Journal of Gastroenterology showed that correcting magnesium deficiency improved constipation symptoms within 46 weeks in 75% of patients

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The practical implication: refrigerate, use within the labeled shelf life, and avoid exposing the vial to repeated temperature fluctuation

In 2021, Mayo Clinic researchers wrote that "their [GLP-1 agonists and analogs] effects are mediated, at least in part, by retardation of gastric emptying" 10 the hallmark of gastroparesis

However, by slowing stomach emptying, semaglutide may reduce the speed at which levothyroxine moves through the digestive tract