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In a 2001 study published in Endocrinology , Heffernan and colleagues reported that chronic AOD-9604 administration reduced body weight gain, decreased adipose tissue mass, and increased fat oxidation in obese mice without altering IGF-1 levels or glucose metabolism effects that were abolished in beta3 adrenergic receptor (3-AR) knockout mice, implicating 3-AR signaling as the mechanism of action [1]

While Lipo injections aid in fat metabolism and weight reduction, complementing them with a nutritious diet and regular physical activity can boost overall outcomes

This chain of events fails to occur in the corticosteroids animals after initial inflammation inhibition (Sikiric et al., 2003)

10.4254/wjh.v12.i5.184 37 KonosicS.PetricevicM.IvancanV.KonosicL.GoluzaE.KrtalicB.et al (2019)