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First, it was reported that the mechanism of C-cell transformation in rodents is by activation of the GLP-1 receptor on the C cell, and a study has shown that GLP-1 receptor stimulation is a better predictor of C-cell hyperplasia than plasma drug concentrations of exenatide and liraglutide (66, 67)

Additionally, magnesium plays a role in muscle function, bone health, and neurological processes, making it a nutrient of broad clinical significance for patients managing chronic metabolic conditions

Li Q, et al

Answer: The standard protocol is 1x weekly at the same time (e.g., always Monday morning)