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J Rheumatol 40(7):10891096 Kyoung-Jin M, Kyounghwa C, Taeg KK (2011) Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells

A significant increase in serum levels of the inflammatory factors IL-1B, TNF-a, and IL-6 was found in hemoglobin-injected mice, whereas the use of inflammatory vesicle inhibitors significantly reduced the levels of hemoglobin-induced inflammatory factors

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Abdolmaleky et al., 2019

Melatonin treatment prevents apoptosis and mitochondrial damage caused by hydrogen-peroxide in retinal pigmented epithelial cells via the activation of melatonin through the MT1 receptor 89