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Not only that, the tumor suppressor gene (TUSC2) encoding a multi-kinase inhibitor delivered through nanovesicles can not only increase circulating and spleen NK cells but also significantly enhance anti-tumor activity and immune response by activating NK cells in combination with anti-PD-1 therapy (86)

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609 PARP inhibitor Actovegin: Actovegin ameliorated sensory nerve conduction velocity (SNCV) and IENFD of experimental DN via mechanisms involving suppression of PARP activation