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Unlike dual-agonist compounds, Retatrutide also activates the glucagon receptor, giving it a unique pharmacological profile for metabolic research
Before GLP-1s like Ozempic were approved, earlier trials tested a range of doses and found that lower doses produced some weight loss and blood sugar improvements
The same study showed that patients taking higher doses and remaining adherent achieved weight loss comparable to clinical trials
Common side effects include mild nausea, diarrhea, or decreased appetite, which often subside as your body adjusts to the medication
How much weight a person loses on GLP-1 agonists depends on many factors, including genetics and how they respond to the drugs
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