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doi: 10.1038/sj.cdd.4401389

Moreover, overexpression of specific GSTs can also affect chemoresistance, whereas polymorphisms that decrease GST activity are associated with a high risk of developing cancer [72]

What's clear: if you experience what appears to be accelerated aging, with deepening wrinkles, increased sagging, or loss of firmness after starting GHK-CU, you should pause your protocol and reassess