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Description

In contrast, dulaglutide alone or in the presence of phosphodiesterase inhibitor rolipram up to 100 nM failed to exert a positive inotropic effect in isolated electrically paced (1 Hz) mouse left atrial preparations and did not increase the beating rate of spontaneously beating mouse right atrial preparations

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Serious adverse effects have not shown up in the research literature

Increasing clinical research and emerging approvals for GLP-1 therapies in younger populations are enabling safer and more effective treatment options for adolescents

Lebrun, L